I was so disappointed when I realized I couldn't profile on OSX without a kernel patch. I wonder if there is any path towards enabling that in the future.
To be fair, that's not always been the case. Last time I tried the profiler under OS X, it all seemed to work, but the actual figures produced by the profiler were nonsense. Other platforms seemed unaffected. That was quite a while ago. If they've fixed it, then great.