I also recommend the followup videos that continue looking into the theory he discussed in episode 63 (your [1]). In particular, episode 69's discussion[2] of glutathione in existing research related to oxidative stress is very interesting. Comparisons are made to acetaminophen (tylenol) toxicity. A very plausible hypothesis is presented that high dose NAC (N-Acetylcysteine) might be a treatment for (some of) COVID-19's worst effects.
NAC is obviously interesting as an antioxidant, but MedCram found a few papers that suggest it might also be important as a way to break the disulfide bonds cross-lining von Willebrand factor that seems to be causing a strokes and other thrombosis-related problems in the worst COVID-19 patients.
Obviously this is all very speculative an turning these hypothesis into something practically useful will require a lot of work. However, as someone with multiple of the serious risk factors[3] for COVID-19, the last few months has mostly been hoping I can avoid dying from the virus before a vaccine is available. The ACE2/glutathione/NAC hypothesis is the first time 3rd option - an effective treatment - has seemed... plausible.
I also recommend the followup videos that continue looking into the theory he discussed in episode 63 (your [1]). In particular, episode 69's discussion[2] of glutathione in existing research related to oxidative stress is very interesting. Comparisons are made to acetaminophen (tylenol) toxicity. A very plausible hypothesis is presented that high dose NAC (N-Acetylcysteine) might be a treatment for (some of) COVID-19's worst effects.
NAC is obviously interesting as an antioxidant, but MedCram found a few papers that suggest it might also be important as a way to break the disulfide bonds cross-lining von Willebrand factor that seems to be causing a strokes and other thrombosis-related problems in the worst COVID-19 patients.
Obviously this is all very speculative an turning these hypothesis into something practically useful will require a lot of work. However, as someone with multiple of the serious risk factors[3] for COVID-19, the last few months has mostly been hoping I can avoid dying from the virus before a vaccine is available. The ACE2/glutathione/NAC hypothesis is the first time 3rd option - an effective treatment - has seemed... plausible.
[2] https://www.youtube.com/watch?v=Dr_6w-WPr0w
[3] diabetes, heart failure and cardiomyopathy from too many years of high-BP and bad sleep apnea (AHI=148)