Sure, and then the upstate counties vote to secede, and the state legislature, dominated by the population center they are trying to secede from says no, and under the Constitution that’s explicitly, unambiguously the ball game, even if you have a friendly federal Congress that would have been willing to approve it.
Barring ratification of a federal Constitutional Amendment stripping the requirement for states to approve any erection of new states using all or part of the land of an existing state, none of these “secession from a state to form a new state or join an adjacent state motivated mainly by partisan interests hostile to the dominant parry of the state being seceded from” moves is ever going to go anywhere.
Every few years some Republican assemblyman proposes splitting “downstate” NY from “upstate”. (itself a matter of debate in some quarters)
It gets some play with the AM radio crowd, than someone shows the guy the math, and they go back to some other issue.