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There is no scientific consensus that naturally acquired immunity gives better protection than vaccines.

Two facts that are trending toward consensus in the scientific literature:

A) Naturally infected individuals who recover will acquire robust and durable immunity [1][2]

B) Natural infection induces an immune response that is mostly similar but slightly different than the immune response induced by vaccination. The primary differences can be summarized as: naturally infected individuals have nucleocapsid protein antibodies whereas vaccinated individuals do not, and vaccinated individuals have an immune response highly targeted toward the spike protein RBD. [3][4][5]

In summary many people hypothesize that natural infection is better because it induces a broader and more balance antibody response, but the literature has not established consensus that this is necessarily "better" in terms of health outcomes for individuals.

[1] SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans https://www.nature.com/articles/s41586-021-03647-4.pdf

[2] Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells https://www.cell.com/cell-reports-medicine/fulltext/S2666-37...

[3] Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination https://www.cell.com/immunity/fulltext/S1074-7613(21)00308-3

[4] Distinct SARS-CoV-2 Antibody Responses Elicited by Natural Infection and mRNA Vaccination https://www.biorxiv.org/content/10.1101/2021.04.15.440089v4

[5] Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection https://pubmed.ncbi.nlm.nih.gov/34103407/



> In summary many people hypothesize that natural infection is better because it induces a broader and more balance antibody response, but the literature has not established consensus that this is necessarily "better" in terms of health outcomes for individuals.

Great summary - I have seen no evidence that natural immunity is better. The opposite could be true. A nucelocapsid-specific immune response cannot be used to kill live virus (the nucleocapsid is not accessible for binding on the surface of a live virus). This means natural immunity will result in an intense off-target immune response (in addition to an intense on-target one for the spike). That off-target response elevates the chances of collateral tissue damage (cytokine storm).




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