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So "[3]" is the only citation you give that addresses vaccine escape and it is about how it doesn't happen that often.

Nice work.



If you read beyond the title you'll find that [3] outlines the conditions for vaccine escape and gives many broad examples of antibiotic and antiviral resistance. [1][2] also discuss vaccine escape in detail, but you won't find that out from the title.


Antibiotic resistance is pretty different than vaccine escape.

I wouldn't say [1] goes into any particular detail.

Nor does [2]. It says it can happen.


The evolutionary process is the same...

1) A population of virus or biotics has genetic diversity and mutations through generations when reproducing.

2) Some pressure is put on its survival (antibiotics, vaccines).

3) Those in the population that survive better (with the new pressure introduced) proliferate more than those in the population that didn't survive or thrive as much.

4) You end up with a population more resistant or immune to the chosen selective pressure initially used on it.




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