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Vortioxetine (Trintellix) is expensive as fuck, most insurance plans have it under multiple restrictions (step therapy (ST), prior auth (PA), others). They have a manufacturer discount card to take off $100 max but if your prescription benefits don't kick in until after you're deductible you will max out every year pretty quickly. I just paid $900 for a 3 month supply.

But... Anecdotally, it does have less sexual side effects than escitalopram (Lexapro), and helps about the same amount with anxiety as escitalopram (Lexapro), though maybe a little bit less effective at that.



Have you been on venlafaxine before? If so, how would you compare it to escitalopram, not in terms of sexual side effects but in terms of efficacy with anxiety.


Ah, I haven't been on venlafaxine before so I wouldn't be able to comment. Sorry. Only escitalopram and vortioxetine


Yeah, both of those medications are criminally expensive.




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