It’s an interesting area. It has the opportunity to really bloom but has a couple issues. Climate sucks, it’s cold even for Northeastern standards. The cities all have urban issues like crime, not many upstate cities have really become cute and desirable. That’s mostly the smaller or mid sized towns.
I grew up nearby. Being just downwind of Lake Ontario, Syracuse gets 10 feet of snow per winter. [0] If you're susceptible to seasonal depression, it's a rough place to live. Just 50 miles south (around Ithaca / Elmira / Binghamton), the winters get milder, still dark but less cold and snow.
For decades, the region has wanted for STEM employment opportunities. (It's the rust belt, a lot of industry moved away.) I get the impression Rochester weathered it better than Syracuse, even after the downfall of Kodak. Rochester feels a little more vibrant to visit. That said, to the extent Micron is willing to train people, I imagine they'll have an easier time hiring in Syracuse than a lot of other places.
As a reference, Boston averages 60 inches, which would put it at the lowest scale on this map. So, even the milder regions are still quite cold and snowy!