In hopes that this helps others. I have had terrible reflux for the last ~10 years. 10-15 tums a day every day for years. About 4 months ago I started taking a scoop of glutamine (the workout supplement / amino acid) powder in water at night before bed (not sure if the timing of when it's taken matters). 2 weeks later and my heartburn/reflux was essentially gone and has stayed gone. I take maybe 1 tums a week now. Many weeks it's 0.