>Could a Neuroscientist Understand a Microprocessor?
>We show that the [neuroscience experimental] approaches reveal interesting structure in the data but do not meaningfully describe the hierarchy of information processing in the microprocessor. This suggests current analytic approaches in neuroscience may fall short of producing meaningful understanding of neural systems, regardless of the amount of data.
Nothing in biology is as regular and systematic as a microprocessor. Scientists study biology using round-about approaches because there is nothing else available.
This is a silly argument. It presupposes that meaningful knowledge about neurons is structured similarly to knowledge about microprocessors, which does not have to be the case since neurons aren’t structured like microprocessors.
This paper, and its precursor 'Could a Biologist Fix a Radio?' mentioned by bschne, come across as somewhat smug and wiser-than-thou. While they do a good job in showing the difficulty of gathering useful information about complex biological systems, they tend to underestimate what human ingenuity can do with just that information which can be gained experimentally. This was demonstrated recently by the rapid development of synthetic vaccines against Covid.
https://journals.plos.org/ploscompbiol/article?id=10.1371/jo...
>Could a Neuroscientist Understand a Microprocessor?
>We show that the [neuroscience experimental] approaches reveal interesting structure in the data but do not meaningfully describe the hierarchy of information processing in the microprocessor. This suggests current analytic approaches in neuroscience may fall short of producing meaningful understanding of neural systems, regardless of the amount of data.