Absolutely - YCbCr 4:2:2 and 4:2:0 use different encodings across the lines to balance bandwidth. Complexity then continues to stack with deep colour pixel packing. There's a beautiful pocket of simplicity for RGB 4:4:4 8bpc which is essentially a direct digital encoding of ye oldy RGBHV signals. More than OK for any retro-comp needs, and a fun starting point for general hacking.