GLP1 analogs could help. They can cross the blood–brain barrier and stimulate th... | Hacker News

Hacker Newsnew | past | comments | ask | show | jobs | submit

		patrickhogan1 on March 20, 2024 \| parent \| context \| favorite \| on: Root cause of Alzheimer's may be fat buildup in br... GLP1 analogs could help. They can cross the blood–brain barrier and stimulate the GLP1 receptor in the brain.[1] There is also research showing improvement in Alzheimer's disease symptoms. [2] [1] https://pubmed.ncbi.nlm.nih.gov/11931352/ [2] https://www.sciencedirect.com/science/article/pii/S221287782...

arcticbull on March 20, 2024 [–]

GLP-1s definitely cross the blood-brain barrier - work by affecting the GABAergic CNS and making you not hungry so you stop eating and lose weight. They don't independently do anything to make you slimmer. Basically what you're suggesting is people lose weight, which, I agree.

Consider applying for YC's Summer 2026 batch! Applications are open till May 4
Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact