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Per the Nature paper, this fat is believed to be part of an immune system response and not related to your intake or total body fat. It is also far from clear that eliminating the production or use of this fat during a microbe invasion would lead to more or less dementia down the road (a good reminder that clinical trials are useful and also risky). This work shows a very refreshing and solid hypothesis and lots of people work on it, but it’s not reason to start changing diets.


Yeah, I almost wish I hadn’t asked given the comments. Really points at an interesting mechanism though. Hopefully this means some kind of preventative or even treatment is possible.




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