May I introduce you to our lord and saviour, Nix and it's most holy child nixpkgs! With only a small tithing of your sanity and ability to Interop with any other dependency management you can free yourself of all dependency woes forever!
Except python builders in nixpkgs are really brain damaged because of the writers ways they inject search path which for example breaks if you try to execute a separate python interpreter assuming same library environment...
Within the holy church of Nix the sect of Python is troubled one, it can however be tamed into use via vast tomes of scripture. Sadly these times can only be written by those you have truly given their mind and body over to the almighty Nix.
Nix is really the best experience I've had with Python package management but only if all the dependencies are already in nixpkgs. If you want to quickly try something off github it's usually a pain in the ass.
[] For various broad* definitions of forever.
[*] Like, really, really broad**
[**] Maybe a week if you're lucky