If the first part of your description is true, then the second needs corrected by replacing the "not...or..." with "therefore...and...".

"Insane from frustration" explains, rather than contradicts, "unpalatable" and "toxic".

People generally do not want to have an insane, frustrated partner.

It's literally enough to sip the surrounding water, it's that easy. Truly toxic frustrated people never have problem with finding sexual partners.