Undoubtedly. If you go poking around most any security product (the product I was referring to was not in the EDR space,) you'll see these sorts of issues all over the place.
It does not have to be the way it is. Security vendors could do a much better job testing and red teaming their products to avoid bypasses, and have more sensible defaults.
The file size problem is still an issue for many big name EDRs.