It might be a fun project to create a UI for use with low refresh displays. Maybe have config options for super low refresh rates, color calibration for the new eink displays and adjust the scroll step size. No mouse pointer, just keyboard shortcuts.
I dream of such a lo-fi UI: no animations, no redundant elements, no individually different look&feel for every app - only the information you really need, displayed where and when it really makes sense, updated when necessary, formatted uniformly.
In fact there already are some projects of eInk-orientd OSes (e.g. MuditaOS). I don't know how good they really are though.