Run a profit? What does that mean? What profitable business is currently available for an aeronautics and space agency that was never about making "profit".
The US government isn’t a business. In fact the current attack on it by Magats is because businesses want part of their pie to turn into a business, not because it will help or empower the people or because the programs cost too much. They are doing it because they want to charge you more. They want to charge you for your comfortable American excess that you already paid for with tax dollars. They want to double dip, have the government subsidize the business with your tax dollars then charge you again to get the value out of it.
There is no sense in trying to treat the government like a business.