This comes up a lot, and exercise and diet surely do work. But the notion of set points is also real and well studied. Once you become overweight and especially obese, your body does all sorts of crazy things to try and maintain that weight. Modulating the metabolism, sleepiness, energy levels etc. The percentage of people who have been obese and returned permanently to a healthy weight through diet and exercise is small enough that if it were a drug, people wouldn't even try it.
People talked about glp drugs moving the set point, I don't know of any research supporting that. It seems like stopping the drug usually adds the weight back. And they are not without risks. But obesity is worse.
You are spot on about American food products. They are calorie rich and nutrient poor. But the obesity problem has spread outside America now. I read one journal article suggesting the spread pattern was more like what you see with the introduction of an unrecognized dangerous chemical, or even a mildly contagious pathogen. Whether it is some odd gut biome pathogen, a weird food additive, or if the chemical is how we grow food itself, the problem isn't contained.
People talked about glp drugs moving the set point, I don't know of any research supporting that. It seems like stopping the drug usually adds the weight back. And they are not without risks. But obesity is worse.
You are spot on about American food products. They are calorie rich and nutrient poor. But the obesity problem has spread outside America now. I read one journal article suggesting the spread pattern was more like what you see with the introduction of an unrecognized dangerous chemical, or even a mildly contagious pathogen. Whether it is some odd gut biome pathogen, a weird food additive, or if the chemical is how we grow food itself, the problem isn't contained.