The Target hack a month back effected my wife. Paying with bitcoin would have removed the possibility of her account being compromised shifting the burden to the retailer. All kinds of possibilities are there to mitigate that risk: cold storage wallets, third party services. Some other accounting implication off the top of my head: create a new payment address for each day, month, or year and automatically reconcile an accounts based on wallet address.

I imagine banks and other bitcoin service venders will solve the charge back issue or 3rd party arbitrators will be common with this: https://en.bitcoin.it/wiki/Contracts#Example_2:_Escrow_and_d...