Because it's clear there isn't a lot of expertise in this thread, I'd like to make clear that nobody should be doing the cinnamon challenge based on these results, or the results of the authors' previous study on the topic. So far, the authors have some interesting data from cell lines and now a mouse model of PD. Specifically, the mouse model is generated by chemical intoxication with a molecule called MPTP, which results in damage to dopaminergic cells in the substantia nigra, the region of the brain whose degeneration is predominantly implicated in the etiology of PD. There is good reason to be skeptical about whether this animal model of the disease is clinically relevant to sporadic PD seen in patients. Furthermore, dramatic results seen in a very obscure journal (i.e. not a mainline journal for neurodegenerative research) should generally result in knee-jerk skepticism until others repeat the work and a more significant review process has taken place. It should go without saying that there have been many compounds in the past two decades to show some interesting results at a preclinical stage that have not passed muster when moving to real patients.